LABEX PUBLICATIONS 2018
An intermediate level of CD161 expression defines a novel activated, inflammatory, and pathogenic subset of CD8+ T cells involved in multiple sclerosis
Nicol B, Salou M, Vogel I, Garcia A, Dugast E, Morille J, Kilens S, Charpentier E, Donnart A, Nedellec S, Jacq-Foucher M, Le Frère F, Wiertlewski S, Bourreille A, Brouard S, Michel L, David L, Gourraud PA, Degauque N, Nicot AB, Berthelot L, Laplaud DA
J Autoimmun. 2018 Mar;88:61-74 - Download full text
Association of Defective Regulation of Autoreactive Interleukin-6-Producing Transitional B Lymphocytes With Disease in Patients With Systemic Sclerosis
Taher TE, Ong VH, Bystrom J, Hillion S, Simon Q, Denton CP, Pers JO, Abraham DJ, Mageed RA
Arthritis Rheumatol. 2018 Mar;70(3):450-461 - Download full text
B cell subset distribution is altered in patients with severe periodontitis
Demoersman J, Pochard P, Framery C, Simon Q, Boisramé S, Soueidan A, Pers JO
PLoS One. 2018 Feb 15;13(2):e0192986 - Download full text
B cells in operational tolerance
Chesneau M, Danger R, Soulillou JP, Brouard S
Hum Immunol. 2018 May;79(5):373-379 - Download full text
Increased degradation of ATP is driven by memory regulatory T cells in kidney transplantation tolerance
Durand M, Dubois F, Dejou C, Durand E, Danger R, Chesneau M, Brosseau C, Guerif P, Soulillou JP, Degauque N, Eliaou JF, Giral M, Bonnefoy N, Brouard S
Kidney Int. 2018 May;93(5):1154-1164
The roles of CSFs on the functional polarization of tumor-associated macrophages
Jeannin P, Paolini L, Adam C, Delneste Y
FEBS J. 2018 Feb;285(4):680-699 - Download full text
Impact on early outcomes and immune reconstitution of high-dose post-transplant cyclophosphamide vs anti-thymocyte globulin after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation
Retière C, Willem C, Guillaume T, Vié H, Gautreau-Rolland L, Scotet E, Saulquin X, Gagne K, Béné MC, Imbert BM, Clemenceau B, Peterlin P, Garnier A, Chevallier P
Oncotarget. 2018 Jan 27;9(14):11451-11464 - Download full text
HLA-DR expression in neonates after cardiac surgery under cardiopulmonary bypass: a pilot study
Chenouard A, Braudeau C, Cottron N, Bourgoin P, Salabert N, Roquilly A, Josien R, Joram N, Asehnoune K
Intensive Care Med Exp. 2018 Jan 11;6(1):1 - Download full text
Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome
Danger R, Royer PJ, Reboulleau D, Durand E, Loy J, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Gomez C, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Foureau A, Pison C, Koutsokera A, Nicod LP, Brouard S, Magnan A; COLT and SysCLAD Consortia
Front Immunol. 2018 Jan 11;8:1841. - Download full text
Fate of transplanted lungs is controlled by immune cells encounter within pulmonary allografts
Degauque N
Am J Transplant. 2018 Jan;18(1):9-10 - Download full text
Breakdown of immune tolerance in AIRE-deficient rats induces a severe APECED-like auto-immune disease
Jason Ossart, Anne Moreau, Elodie Autrusseau, Séverine Ménoret, Jérôme C. Martin, Marine Besnard, Laure-Hélène Ouisse, Laurent Tesson, Léa Flippe, Kai Kisand, Pärt Peterson, François-Xavier Hubert, Ignacio Anegon, Régis Josien and Carole Guillonneau
J. Immunol. , July 2018
HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition
N. Jouand, C. Bressollette-Bodin, N. Gérard, M. Giral, P. Guérif, A. Rodallec, R. Oger, T. Parrot, M. Allard, A. Cesbron-Gautier, N. Gervois and B. Charreau
PLOS Pathogens April 30, 2018 - Download full text
Comparison of Immuno-PET of CD138 and PET imaging with 64CuCl2 and 18F-FDG in a preclinical syngeneic model of multiple myeloma
Clément Bailly, Sébastien Gouard, Marie Lacombe, Patricia Remaud-Le Saëc, Benjamin Chalopin, Mickaël Bourgeois, Nicolas Chouin, Raphaël Tripier, Zakaria Halime, Ferid Haddad, Alain Faivre-Chauvet, Françoise Kraeber-Bodéré, Michel Chérel and Caroline Bodet-Milin
Oncotarget, Jan 2018 - Download full text
Generation of immunodeficient rats with Rag1 and Il2rg gene deletions and human tissue grafting models
Séverine Ménoret, Laure-Hélène Ouisse, Laurent Tesson, Frédéric Delbos, Delphine Garnier, Séverine Remy, Claire Usal, Jean-Paul Concordet, Carine Giovannangeli, Vanessa Chenouard, Lucas Brusselle, Emmanuel Mérieau, Véronique Nerrière-Daguin, Franck Duteille, Frédérique Bellier-Waast, Alexandre Fraichard, Tuan H. Nguyen and Ignacio Anegon
Transplantation. 2018 Apr 23.
Fine-mapping the interaction between DC-SIGN and the cytomegalovirus envelope glycoprotein B
C. Chéneau, F. Coulon, V. Porkolab, F. Fieschi, S. Laurant, D. Razanajaona-Doll, J.-J. Pin, E. Maria Borst, M. Messerle, C. Bressollette-Bodin, F. Halary
J Infect Dis. 2018 Apr 10 - Download Full Text
Multiplex CRISPR/Cas9 system impairs HCMV replication by excising an essential viral gene
J. Gergen, F. Coulon, A. Creneguy, N. Elain-Duret, A. Gutierrez, O. Pinkenburg,E. Verhoeyen, I. Anegon, T. H. Nguyen, F. A. Halary, F. Haspot
Plos One, Feb 2018 - Download Full Text
CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair
M. Charpentier, A. H. Y. Khedher, S. Menoret, A. Brion, K. Lamribet, E. Dardillac, C. Boix, L. Perrouault, L. Tesson, S. Geny, A. De Cian, J. M. Itier, I. Anegon, B. Lopez, C. Giovannangeli & J. P. Concordet
Nature Communications, March 2018 - Download Full Text
C-type lectin-like receptors as emerging orchestrators of sterile inflammation represent potential therapeutic targets
E. Chiffoleau
Frontiers in Immunology, Jan 2018
Tolerogenic dendritic cells in solid organ transplantation: where do we stand?
E. Marin, M.C. Cuturi, A. Moreau
Frontiers in Immunology, Fev 2018
Ex vivo expanded human non-cytotoxic CD8+CD45RClow/- tregs efficiently delay skin graft rejection and GVHD in humanized mice
S. Bézie, D. Meistermann, L. Boucault, S. Kilens, J. Zoppi, E. Autrusseau, A. Donnart, V. Nerrière-Daguin, F. Bellier-Waast, E. Charpentier, F. Duteille, L. David, I. Anegon & C. Guillonneau
Frontiers in Immunology, Jan 2018
C-type lectin-like receptors as emerging orchestrators of sterile inflammation represent potential therapeutic targets
E. Chiffoleau
Frontiers in Immunology, Jan 2018
High circulating CD4+CD25hiFOXP3+ T cell subpopulation early after lung transplantation is associated with development of bronciolitis obliterans syndrome
M. Durand, P. Lacoste, R. Danger, L. Jacquemont, C. Brosseau, E. Durand, G. Tilly, J. Loy, A. Foureau, P.-J. Royer, A. Tissot, A. Roux, M. Reynaud-Gaubert, R. Kessler, S. Mussot, C. Dromer, O. Brugière, J.-F. Mornex, R. Guillemain, J. Claustre, N. Degauque, A. Magnan, S. Brouard & COLT and SysCLAD Consortia
J Heart Lung Transplant, 2018 - In press
Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
S. Kilens, D. Meistermann, D. Moreno, C. Chariau, A. Gaignerie, A. Reignier, Y. Lelièvre, M. Casanova, C. Vallot, S. Nedellec, L. Flippe, J. Firmin, J. Song, E. Charpentier, J. Lammers, A. Donnart, N. Marec, W. Deb, A. Bihouée, The Milieu Intérieur Consortium, C. Le Caignec, C. Pecqueur, R. Redon, P. Barrière, J. Bourdon, V. Pasque, M. Soumillon, T. S. Mikkelsen, C. Rougeulle, T. Fréour & L. David
Nat Commun 2018, 9 - Download full text
Notch signaling triggered via the ligand DLL4 impedes M2 macrophage differentiation and promotes their apoptosis
S. Pagie, N. Gérard & B. Charreau
Cell Communication and Signaling, Jan 2018 in press
A Standardized FlowCytometry Procedure for the Monitoring of Regulatory T Cells in Clinical Trials
F. Pitoiset, M. Barbié, G. Monneret, C. Braudeau, P. Pochard, I. Pellegrin, J. Trauet, M. Labalette, D. Klatzmann, M. Rosenzwajg
Cytometry Part B, 2018 - - Download full text
PD-1 expression on tumor-specific T cells: Friend or foe for immunotherapy ?
Sylvain Simon and Nathalie Labarriere
OncoImmunology, Volume 7, 2018 - Issue 1 - Download full text